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AI Health·Pre-Seed·San Francisco, CA

Senior Software Engineer

at NickelAI Health
Location
San Francisco, CA
Salary
$210,000 - $240,000
Type
Full-Time
About Nickel
Nickel's mission is to add ten healthy years to your life — specifically to democratize billionaire-quality longevity care at employer-plan cost. The best doctors in the world spend extraordinary time with their patients, integrate aggressive diagnostics and longevity science into a tailored journey, and build the business model around the patient rather than insurance. Nickel is bringing that standard of care to everyone. The product architecture is unusual and technically ambitious: - Sovereign on-premise hardware: a GPU-equipped box that lives inside the physician's clinic. Patient data never leaves the practice. Sub-second local compute - Software stack: integrates with EHRs (Epic, Athena), wearables (Apple Watch, Samsung, Fitbit, Aura Ring), lab work, and imaging systems including Prenuvo full-body MRI - In-clinic camera and ambient voice: during appointments, the box captures body signals (skin flush, fatigue, posture) alongside voice — synthesizing multi-modal signals into a physician-facing recommendation - Human-in-the-loop AI: the AI generates concierge-medicine recommendations. The physician reviews and approves before anything reaches the patient. Nickel does not replace physicians; it 10x's their throughput - Marketplace layer: patients get concierge recommendations across a curated provider network (cryotherapy, red light therapy, nutrition, supplements, physical therapy, adjacent scans). Nickel monetizes the marketplace referrals The business dual-benefit: physicians can serve more patients at a higher standard of care. Patients get more services for the same spend. Nickel captures value on the marketplace referrals plus the hardware/software subscription. Stage and traction: - $30M pre-seed raise - Team of 20: ~10 hardware engineers in Shenzhen (China), plus stateside leadership from NVIDIA, Nike, NASA JPL, Samsung Health, plus ZS Associates - Design team and showroom in Venice, LA - Aug 1, 2026 soft launch (internal / limited) - Nov 1, 2026 consumer launch (public) - Currently quasi-stealth
Pre-Seed • 11 - 50
Stage & size
AI Health
Industry
2025
Founded
About This Role

Nickel is hiring a Senior Software Engineer to build the physician-facing dashboard, patient-facing mobile / web application, data pipelines, and infrastructure that runs on and around the on-prem box.

The bar is high. Nickel's leadership team has 20-25+ years of experience at NVIDIA, Nike, NASA JPL, and Samsung Health.

The hire owns at least one of the following areas at real depth:

  • Distributed computing and systems: Kubernetes, large-scale orchestration, reliability engineering at load, architecting data layers, powering fast and intelligent applications, ensuring reliable / scalable / secure data pipelines with clean APIs
  • GPU acceleration: CUDA kernels, NVIDIA stack, performance optimization in constrained hardware environments (direct match for the on-prem box)
  • Retrieval-augmented generation and knowledge systems: RAG pipelines, vector databases, LLM integration in production
  • High-fidelity 3D graphics and visualization: real-time rendering, clinical or spatial data visualization
  • Front end (UI/UX) development: responsive, performant end-user interfaces across web and native mobile, translating high-fidelity design specs into clean, maintainable code, visual precision, fluid animations, platform-native feel
  • Systems orchestration: containerization, edge compute, firmware and software deployment pipelines in non-datacenter environments (the physician-clinic edge deployment is core to Nickel)

What Nickel looks for in your background:

  • Systems you built, owned, and ran in production under real load
  • Decisions you made on your own, without a playbook
  • Something you built because it was interesting, not because it was assigned — an open source project people actually use, a competition, a hard problem you just wanted to solve
  • Curiosity that shows up outside your job description

Requirements

  • 7-12 years of professional engineering experience
  • Real depth in at least one of the six expertise areas above
  • Production shipping track record
  • Autonomous builder DNA
  • Thick skin under pushback — Constant push-and-pull with leadership is baked into the culture
  • Mission alignment on longevity / concierge medicine
  • Available to start ASAP

Strong Bonuses

  • Open-source shipping track record with real README depth — not just repos, but visible intent and problem framing
  • Competition wins — ICPC, IOI, hackathon top prizes
  • Personal side projects that document escalation
  • Prior work at a company that shipped hardware + software integrated products — Tesla, Apple hardware, Meta AR/VR, Peloton, DJI, Ring
  • Direct experience with sovereign on-prem AI deployments — federal, healthcare, financial services
  • Experience with FDA-regulated / HIPAA-regulated environments
Job Details
Experience
7-12 years
Salary
$210,000 - $240,000
Equity
Yes
Visa Sponsorship
No
Employment Type
Full-Time
Benefits & Perks
Full Healthcare Coverage
401(k)
Relocation Package
Green Flags
NVIDIA / Meta AI / Cerebras / OpenAI / Anthropic / Tesla / SpaceX / Roblox background
Personal side project that documents technical escalation
Open-source repo with real README depth — problem framing, why-built, adoption metrics
Red Flags
Consultancy background (TCS / Accenture / Infosys / Wipro / Cognizant)
Walmart engineering / retail tech / Big 4 tech consulting
Pure private-repo builder with no visible shipping signal

Required Candidate Q&A

Question 1
Are you a US citizen?
Question 2
Are you SF Bay-based or willing to relocate immediately, and able to be in-person 3+ days/week?
Question 3
Why are you looking to leave your current role?

Candidate scorecard

· 10 criteria
7-12 years of production engineering experience
Real depth in at least one of the six named expertise areas
Shipped product at scale (not just repos)
Rounds · Confidential to recruiting partners · Last refreshed Sep 9, 2026